Muscle Loss Risk
Estimate lean-mass risk during GLP-1 weight loss and get personalized recommendations to preserve muscle.
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We reviewed these telehealth providers for GLP-1 access, pricing, and clinical quality. All require a medical evaluation before prescribing.
Why muscle preservation matters on GLP-1s
Weight loss isn’t just “fat loss.” When the scale goes down, the change can include body fat, glycogen/water, and lean mass. In many weight-loss studies, a meaningful portion of weight lost can come from lean mass if muscle-preserving behaviors aren’t prioritized. A commonly cited baseline is ~25% lean mass—but your actual ratio depends on your training, protein, and how fast you lose.
The good news: you have leverage. Resistance training gives your body a reason to keep muscle. Protein provides building blocks for repair and maintenance—especially important when appetite is reduced. And keeping your loss rate in a reasonable range can reduce the “need” for your body to break down lean tissue.
Use this calculator as a risk screen, not a diagnosis. If you’re flagged as high risk, the fix is usually straightforward: eat more protein, lift weights 2–3 times per week, and consider a slightly slower target loss rate.